MassChallenge

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Accelerators
Founder-focused & industry
agnostic
Industry-specific for
mid-to-late stage startups
A variety of mentorship & industry
focuses for all stages
Driving innovation & startup
ecosystem development
Partnerships
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About
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Home

WE BACK THE RARE HUMANS
WITH THE GRIT TO SOLVE THE
TOUGHEST CHALLENGES.

Accelerating solutions in Healthcare & Life Sciences, Security & Resiliency, Sustainable Food Systems, Climate, and Global Financial Systems.

We back the rare humans with the grit to solve the toughest challenges.

Accelerating solutions in Healthcare & Life Sciences, Security & Resiliency, Sustainable Food Systems, Climate, and Global Financial Systems.

Startups Accelerated
1 +
Follow-on Capital Raised
$ 0 B
Direct Jobs Created
1
Global Partners
1 +

DIFFERENT BY DESIGN

Since 2009, we’ve built a formidable global network and we’re obsessive about giving founders breakthrough access to the people and power that move markets. Corporates, customers, regulators, funders—leaders who understand complexity and help you scale what truly matters.

FOUNDERS

Founders need more than capital. They need access, insight, and relationships that unlock momentum. We accelerate those connections through proven programs, giving you the leverage to move faster and go further.

EXPERTS

Our experts—founders, operators, researchers, and industry leaders—support you at critical inflection points, Their real-world insight sharpens your roadmap: technical, go-to-market, or team. Every connection delivers high-impact access when it matters most.

COLLABORATORS

Our collaborators know progress demands more than optimism. Together, we work to reshape the systems founders rely on, whether capital, policy, and industry, especially where barriers are steepest. We ensure founders have the support they need to reach scale.

WHAT'S HAPPENING AT MASSCHALLENGE?

Here are just a few of the programs currently accepting applications. Don't see a fit? Follow @MassChallenge on LinkedIn to stay up-to-date on new opportunities as they open.

FINTECH • HEALTHCARE & LIFE SCIENCES

MassMutual

What if we could stop fraud before money moves? Make financial advice smarter? Help people live longer, healthier lives? MassMutual is looking for startups rethinking what's possible across finance, technology, and health.

FINTECH

SMU Cox FinTech Accelerator

Connecting fintech startups from around the world with industry experts, financial institutions, and investors to accelerate commercial growth. The hybrid program combines specialized mentorship, corporate engagement, and three immersive experiences in Dallas, Texas.

HEALTHCARE & LIFE SCIENCES

Eli Lilly

Millions of transactions. Thousands of policy changes. What if AI could find what matters before anyone thinks to look? Lilly is exploring smarter ways to protect resources and improve patient access.

CLIMATE • SUSTAINABILITY

MC Switzerland Sustainable Materials Challenge

2027 Sustainable Materials Challenge connects startups with global industry leaders to advance bio-based materials, circular solutions, and technologies that turn waste into value. The goal: lower emissions, better performance, and innovations ready to scale.

REAL WORDS FROM FOUNDERS REDEFINING WHAT'S POSSIBLE.

FEATURED PARTNERS

THANK YOU TO OUR FINANCIAL PARTNER

STAY CONNECTED

Follow MassChallenge for upcoming events, founder stories, and opportunities to get involved.