Featured Entrepreneurs

Since 2010, MassChallenge has accelerated 1,975 startups that have raised more than $4.3 billion in funding, generated more than $2.5 billion in revenue, and created more than 121,000 total jobs. 

Our startups

Be inspired. Search our startups.


Today the 8% of dental implants fail because of bruxism (teeth clenching during sleep). Bruxism is the main cause of mechanical stress on dental implants. Today there are not solutions to reduce the excessive load on implants induced by bruxism. Aesyra develops high-tech dental appliances that actively reduce bruxism forces in a minimally invasive fashion at night time, helping to save 1.3M implants per year. Bruxism is a $3B market and our product will be commercialized starting early 2020.
Aesyra develops a medical device for monitoring and reducing sleep bruxism using biofeedback, helping to save millions of dental implants.

Connect with Aesyra


2018 Finalist Switzerland

Sub industry

Medical Devices


MassChallenge strengthens the global innovation ecosystem by accelerating high-potential startups across all industries, from anywhere in the world.